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BioCellGen-public
sgcocaller
Commits
412415fc
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412415fc
authored
3 years ago
by
Ruqian Lyu
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## sgcocaller: Calling crossovers from single-gamete DNA sequencing reads
Two modules are available in
`sgcocaller`
,
`fmf`
and
`xo`
.
`sgcocaller fmf`
generates the fragment input files for phasing the individual using the
gametes' genotypes along the heterozygous SNPs.
`sgcocaller xo`
call
s
crossovers
in each single
gamete using a Hidden Markov Model.
Two
main
modules are available in
`sgcocaller`
,
phasing and crossover calling.
`sgcocalelr phase`
generate donor haplotype from single-gamete DNA sequencing data.
`sgcocaller xo`
and
`sgcocaller
s
xo`
both
call crossovers
in each single
gamete using a Hidden Markov Model.
`sgcocaller`
processes DNA reads from each single gamete in the aligned and
sorted BAM file for inferring the haplotypes of single gamete genomes that can
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