% Generated by roxygen2: do not edit by hand % Please edit documentation in R/estimate.R \name{estMeanParams} \alias{estMeanParams} \title{Estimate mean parameters} \usage{ estMeanParams(norm.counts, params) } \arguments{ \item{norm.counts}{library size normalised counts matrix.} \item{params}{splatParams object to store estimated values in.} } \value{ splatParams object with estimated values. } \description{ Estimate rate and shape parameters for the gamma distribution used to simulate gene expression means using the 'moment matching estimation' method of \code{\link{fitdist}}. } \examples{ \dontrun{ data("sc_example_counts") norm_ex_counts <- t(t(sc_example_counts) / colSums(sc_example_counts) * median(colSums(sc_example_counts))) params <- splatParams() params <- estMeanParams(norm_ex_counts, params) params } }