% Generated by roxygen2: do not edit by hand % Please edit documentation in R/splat-simulate.R \name{splatSimDropout} \alias{splatSimDropout} \title{Simulate dropout} \usage{ splatSimDropout(sim, params) } \arguments{ \item{sim}{SCESet to add dropout to.} \item{params}{SplatParams object with simulation parameters.} } \value{ SCESet with simulated dropout and observed counts. } \description{ A logistic function is used to form a relationshop between the expression level of a gene and the probability of dropout, giving a probability for each gene in each cell. These probabilities are used in a Bernoulli distribution to decide which counts should be dropped. }