% Generated by roxygen2: do not edit by hand % Please edit documentation in R/pheno-simulate.R \name{phenoSimulate} \alias{phenoSimulate} \title{PhenoPath simulation} \usage{ phenoSimulate(params = newPhenoParams(), verbose = TRUE, ...) } \arguments{ \item{params}{PhenoParams object containing simulation parameters.} \item{verbose}{logical. Whether to print progress messages} \item{...}{any additional parameter settings to override what is provided in \code{params}.} } \value{ SingleCellExperiment containing simulated counts } \description{ Simulate counts from a pseudotime trajectory using the PhenoPath method. } \details{ This function is just a wrapper around \code{\link[phenopath]{simulate_phenopath}} that takes a \code{\link{PhenoParams}}, runs the simulation then converts the output from log-expression to counts and returns a \code{\link[SingleCellExperiment]{SingleCellExperiment}} object. The original simulated log-expression values are returned in the \code{LogExprs} asssay. See \code{\link[phenopath]{simulate_phenopath}} and the PhenoPath paper for more details about how the simulation works. } \examples{ sim <- phenoSimulate() } \references{ Campbell K, Yau C. Uncovering genomic trajectories with heterogeneous genetic and environmental backgrounds across single-cells and populations. bioRxiv (2017). Paper: \url{10.1101/159913} Code: \url{https://github.com/kieranrcampbell/phenopath} }