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Splatter

Splatter is an R package for the simple simulation of single-cell RNA sequencing data. Splatter provides a common interface that has:

  • Functions for estimating simulation parameters
  • Objects for storing those parameters
  • Functions for simulating counts using those parameters

Splatter is built on top of scater and stores simulations in SCESet objects.

Installation.

Splatter can be installed from Github using devtools:

install.packages("devtools")
devtools::install_github("Oshlack/splatter", build_vignettes = TRUE)

Getting started

Once installed the best place to get started is the vignette. Load Splatter, then browse the vignettes:

library(splatter)
browseVignettes("splatter")

This is a detailed document that introduces the main features of Splatter.